6 60241036232424Reads by AI crawlersClaude2ChatGPT4Google · Gemini10Perplexity3Meta AI6Microsoft · Copilot2Amazon3Apple2China (ByteDance, Huawei, Baidu…)4ByteDance (Doubao)4Others24Total60Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
e2/e3Published research associates this genotype with somewhat reduced lifetime risk compared to baseline.
e3/e3The most common genotype. Published research treats this as the baseline (average) risk level.
e3/e4One copy of the e4 allele. Published research associates this genotype with moderately elevated lifetime risk of late-onset Alzheimer's disease compared to baseline.
e4/e4Two copies of the e4 allele. Published research associates this genotype with substantially elevated lifetime risk of late-onset Alzheimer's disease compared to baseline.
This result does not predict whether or when Alzheimer's disease will occur. Talk to a doctor or a genetic counselor about what this means for you and your family.
rs429358-rs7412 is a single position in the genome, in or near the APOE gene. Published research associates it with alzheimer's disease risk (apoe). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs429358-rs7412 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease Risk (APOE), Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does rs429358-rs7412 affect how medicines work?
APOE carries pharmacogenomic findings for Lecanemab and other anti-amyloid antibodies. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs429358-rs7412 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs429358-rs7412 come from?
Corder et al. 1993, Science — gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease. PMID 8346443. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
6 60241036232424Reads by AI crawlersClaude2ChatGPT4Google · Gemini10Perplexity3Meta AI6Microsoft · Copilot2Amazon3Apple2China (ByteDance, Huawei, Baidu…)4ByteDance (Doubao)4Others24Total60Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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