Standard

Cortical surface area

EFCAB5 · rs4291964

What the study found

Who was studied 33,992 European ancestry individuals; replicated in 14,727 European ancestry individuals, 2,943 individuals.

The effect Each copy of the A allele shifted the measure 8.13 lower (95% confidence interval 5.84-10.42); p = 4 × 10−12.

How common The A allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 17, band 17q11.2 — in an intron of EFCAB5.

What each result means

A/A Two copies of the version the research linked to Cortical surface area. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cortical surface area. That is a smaller link than two copies.
G/G No copy of the version the research linked to Cortical surface area. This is the starting point the study compared everyone against.
Source

Questions about rs4291964

What is rs4291964?

rs4291964 is a single position in the genome, in or near the EFCAB5 gene. Published research associates it with cortical surface area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4291964 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4291964 come from?

GWAS Catalog, Science (New York, N.Y.) 2020, PMID:32193296. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cortical surface area (rs4291964). MyGeneLog™. https://www.mygenelog.com/variants/rs4291964

← See all variants