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Vertigo

ZNF91 · rs428549

What the study found

Who was studied 6,199 East Asian ancestry cases, 54,587 East Asian ancestry controls, 48,072 European ancestry cases, 894,541 European ancestry controls.

The effect Each copy of the G allele carried 1.17 times the odds of Vertigo (95% confidence interval 1.123-1.212); p = 3 × 10−44.

How common The G allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 19, band 19p12 — a missense change in ZNF91.

What each result means

A/A No copy of the version the research linked to Vertigo. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Vertigo. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Vertigo. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs428549

What is rs428549?

rs428549 is a single position in the genome, in or near the ZNF91 gene. Published research associates it with vertigo. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs428549 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs428549 come from?

GWAS Catalog, Communications biology 2024, PMID:39174713. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vertigo (rs428549). MyGeneLog™. https://www.mygenelog.com/variants/rs428549

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