Standard
Parent of origin effect on language impairment (paternal)
C14orf21 · rs4280164
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Parent of origin effect on language impairment (paternal) — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Parent of origin effect on language impairment (paternal).
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Parent of origin effect on language impairment (paternal) compared to the general population.
Source
Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment
Nudel R,
Simpson NH,
Baird G,
O'Hare A,
Conti-Ramsden G,
Bolton PF,
Hennessy ER,
Ring SM,
Davey Smith G,
Francks C,
Paracchini S,
Monaco AP
and 2 more — show all
Genes, brain, and behavior · 2014 · PMID 24571439 · open access
Questions about rs4280164
What is rs4280164?
rs4280164 is a single position in the genome, in or near the C14orf21 gene. Published research associates it with parent of origin effect on language impairment (paternal). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4280164 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4280164 come from?
GWAS Catalog, Genes Brain Behav 2014, PMID:24571439. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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