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Transmembrane emp24 domain-containing protein 10 protein levels (SomaScan ID:14038-130)

near LINC02967 · rs4273288

What the study found

Who was studied 199 Shetland Isles origin ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.971 higher (95% confidence interval 0.85-1.09); p = 2 × 10−20.

Where it sits Chromosome 20, band 20p11.21 — between genes, 10.4 kb from LINC02967.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Transmembrane emp24 domain-containing protein 10 protein levels (SomaScan ID:14038-130) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Transmembrane emp24 domain-containing protein 10 protein levels (SomaScan ID:14038-130).
G/G Published research associates this genotype with typical/baseline likelihood of Transmembrane emp24 domain-containing protein 10 protein levels (SomaScan ID:14038-130) — no copies of the reported risk allele.
Source

Questions about rs4273288

What is rs4273288?

rs4273288 is a single position in the genome, in or near the near LINC02967 gene. Published research associates it with transmembrane emp24 domain-containing protein 10 protein levels (somascan id:14038-130). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4273288 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4273288 come from?

GWAS Catalog, Communications biology 2025, PMID:40883583. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Transmembrane emp24 domain-containing protein 10 protein levels (SomaScan ID:14038-130) (rs4273288). MyGeneLog™. https://www.mygenelog.com/variants/rs4273288

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