C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Male-pattern baldness compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Male-pattern baldness.
T/TPublished research associates this genotype with typical/baseline likelihood of Male-pattern baldness — no copies of the reported risk allele.
Nature communications · 2018 · PMID 30573740 · open access
Questions about rs4258599
What is rs4258599?
rs4258599 is a single position in the genome, in or near the GSE1 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4258599 linked to?
On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.
Does having rs4258599 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4258599 come from?
GWAS Catalog, Nat Commun 2018, PMID:30573740. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.