1 4232117223120Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others20Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,820 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.238 lower; p = 7 × 10−18.
How common The T allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 4, band 4q35.2 — in an intron of KLKB1.
What each result means
G/GNo copy of the version the research linked to Metabolic traits. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Metabolic traits. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Metabolic traits. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs4253252 is a single position in the genome, in or near the KLKB1 gene. Published research associates it with metabolic traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4253252 linked to?
On MyGeneLog this position is linked to Blood Metabolite Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs4253252 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4253252 come from?
GWAS Catalog, Nature 2011, PMID:21886157. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 4232117223120Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others20Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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