Standard
Acute lymphoblastic leukemia (childhood)
ARID5B · rs4245595
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Acute lymphoblastic leukemia (childhood) compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Acute lymphoblastic leukemia (childhood).
T/T
Published research associates this genotype with typical/baseline likelihood of Acute lymphoblastic leukemia (childhood) — no copies of the reported risk allele.
Source
Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures
Evans TJ,
Milne E,
Anderson D,
de Klerk NH,
Jamieson SE,
Talseth-Palmer BA,
Bowden NA,
Holliday EG,
Rudant J,
Orsi L,
Richardson E,
Lavis L
and 5 more — show all
PloS one · 2014 · PMID 25310577 · open access
Questions about rs4245595
What is rs4245595?
rs4245595 is a single position in the genome, in or near the ARID5B gene. Published research associates it with acute lymphoblastic leukemia (childhood). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4245595 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4245595 come from?
GWAS Catalog, PLoS One 2014, PMID:25310577. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants