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Trigger finger

LTBP3 · rs4244811

What the study found

Who was studied 2,908 European ancestry cases, 436,579 European ancestry controls; replicated in 1,485 European ancestry cases, 137,185 European ancestry controls.

The effect Each copy of the G allele shifted the measure 6.29 z score higher; p = 3 × 10−10.

Where it sits Chromosome 11, band 11q13.1 — in an intron of LTBP3.

What each result means

A/A No copy of the version the research linked to Trigger finger. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Trigger finger. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Trigger finger. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4244811

What is rs4244811?

rs4244811 is a single position in the genome, in or near the LTBP3 gene. Published research associates it with trigger finger. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4244811 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4244811 come from?

GWAS Catalog, The Lancet. Rheumatology 2022, PMID:36043126. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Trigger finger (rs4244811). MyGeneLog™. https://www.mygenelog.com/variants/rs4244811

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