3 29126123113Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others13Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 22 European ancestry cases, 103 European ancestry controls.
The effect
Each copy of the C allele carried 12.00 times the odds of ALS reversal in amyotrophic lateral sclerosis (95% confidence interval 4.1-34.6); p = 4 × 10−8.
Where it sits Chromosome 4, band 4q12 — in an intron of IGFBP7.
What each result means
C/CTwo copies of the version the research linked to ALS reversal in amyotrophic lateral sclerosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to ALS reversal in amyotrophic lateral sclerosis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to ALS reversal in amyotrophic lateral sclerosis. This is the starting point the study compared everyone against.
rs4242007 is a single position in the genome, in or near the IGFBP7 gene. Published research associates it with als reversal in amyotrophic lateral sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4242007 linked to?
On MyGeneLog this position is linked to Amyotrophic Lateral Sclerosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs4242007 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4242007 come from?
GWAS Catalog, Neurology 2024, PMID:39079071. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 29126123113Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others13Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
ALS reversal in amyotrophic lateral sclerosis (rs4242007). MyGeneLog™. https://www.mygenelog.com/variants/rs4242007