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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 13,342 European ancestry cases, 261,265 European ancestry controls.
The effect
Each copy of the C allele carried 0.91 times the odds of ICD10 O42: Premature rupture of membranes (95% confidence interval 0.89-0.94); p = 5 × 10−10.
Where it sits Chromosome 12, band 12q13.13 — in an intron of SLC4A8.
What each result means
C/CTwo copies of the version the research linked to ICD10 O42: Premature rupture of membranes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to ICD10 O42: Premature rupture of membranes. That is a smaller link than two copies.
T/TNo copy of the version the research linked to ICD10 O42: Premature rupture of membranes. This is the starting point the study compared everyone against.
rs4237901 is a single position in the genome, in or near the SLC4A8 gene. Published research associates it with icd10 o42: premature rupture of membranes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4237901 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4237901 come from?
GWAS Catalog, Nature medicine 2025, PMID:40069456. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
ICD10 O42: Premature rupture of membranes (rs4237901). MyGeneLog™. https://www.mygenelog.com/variants/rs4237901