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Platelet-large cell ratio in pregnancy

STK38 · rs4236051

What the study found

Who was studied 96,333 Chinese ancestry individuals; replicated in 46,394 Chinese ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.201 lower (95% confidence interval 0.18-0.22); p = 4 × 10−92.

How common The T allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 6, band 6p21.31 — in an intron of STK38.

What each result means

C/C No copy of the version the research linked to Platelet-large cell ratio in pregnancy. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Platelet-large cell ratio in pregnancy. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Platelet-large cell ratio in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4236051

What is rs4236051?

rs4236051 is a single position in the genome, in or near the STK38 gene. Published research associates it with platelet-large cell ratio in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4236051 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4236051 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet-large cell ratio in pregnancy (rs4236051). MyGeneLog™. https://www.mygenelog.com/variants/rs4236051

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