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Speech perception in dyslexia

PDGFC · rs4234898

What the study found

Who was studied 200 European ancestry cases; replicated in 186 European ancestry cases.

The effect The reported allele is T; the catalogue records no effect size ; p = 5 × 10−8.

Where it sits Chromosome 4, band 4q32.1 — between genes, 35.2 kb from LOC102724785.

What each result means

C/C No copy of the version the research linked to Speech perception in dyslexia. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Speech perception in dyslexia. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Speech perception in dyslexia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4234898

What is rs4234898?

rs4234898 is a single position in the genome, in or near the PDGFC gene. Published research associates it with speech perception in dyslexia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4234898 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4234898 come from?

GWAS Catalog, Mol Psychiatry 2009, PMID:19786962. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Speech perception in dyslexia (rs4234898). MyGeneLog™. https://www.mygenelog.com/variants/rs4234898

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