0 302221722318Reads by AI crawlersClaude2ChatGPT2Google · Gemini2Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 509,429 European ancestry individuals, 16,962 East Asian, South Asian, Hispanic and African American ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 4 × 10−33.
How common The A allele had a frequency of about 86% in the people studied.
Where it sits Chromosome 3, band 3q27.2 — in an intron of ETV5.
What each result means
A/ATwo copies of the version the research linked to Body mass index and HDL-C (pairwise). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Body mass index and HDL-C (pairwise). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Body mass index and HDL-C (pairwise). This is the starting point the study compared everyone against.
rs4234589 is a single position in the genome, in or near the ETV5 gene. Published research associates it with body mass index and hdl-c (pairwise). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4234589 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs4234589 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4234589 come from?
GWAS Catalog, Nat Metab 2021, PMID:33619380. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 302221722318Reads by AI crawlersClaude2ChatGPT2Google · Gemini2Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index and HDL-C (pairwise) (rs4234589). MyGeneLog™. https://www.mygenelog.com/variants/rs4234589