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Who was studied up to 62,166 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.056 s.d. higher (95% confidence interval 0.04-0.072); p = 5 × 10−12.
How common The G allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 11.6 kb from TSBP1-AS1.
What each result means
A/ANo copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs419132 is a single position in the genome, in or near the HLA-area gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs419132 linked to?
On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.
Does having rs419132 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs419132 come from?
GWAS Catalog, Nature genetics 2015, PMID:25961943. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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