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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 46,685 European ancestry individuals; replicated in 4,765 non-European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.475 lower (95% confidence interval 0.34-0.61); p = 1 × 10−11.
How common The A allele had a frequency of about 27% in the people studied.
Where it sits Chromosome 5, band 5q31.3 — in an intron of HBEGF.
What each result means
A/ATwo copies of the version the research linked to Corpus callosum posterior body area. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Corpus callosum posterior body area. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Corpus callosum posterior body area. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 41188267 · open access
Questions about rs4150214
What is rs4150214?
rs4150214 is a single position in the genome, in or near the HBEGF gene. Published research associates it with corpus callosum posterior body area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4150214 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4150214 come from?
GWAS Catalog, Nature communications 2025, PMID:41188267. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Corpus callosum posterior body area (rs4150214). MyGeneLog™. https://www.mygenelog.com/variants/rs4150214