5 32111722315Reads by AI crawlersClaude1ChatGPT0Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3Others15Total32Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 172,433 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0458 higher (95% confidence interval 0.032-0.059); p = 2 × 10−11.
How common The G allele had a frequency of about 7% in the people studied.
Where it sits Chromosome 17, band 17q21.32 — in an intron of TBX21.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Mean corpuscular volume — no copies of the reported risk allele.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mean corpuscular volume.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mean corpuscular volume compared to the general population.
rs41444548 is a single position in the genome, in or near the TBX21 gene. Published research associates it with mean corpuscular volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs41444548 linked to?
On MyGeneLog this position is linked to Blood Cell Counts, Chronic Rhinosinusitis with Nasal Polyps. The research behind each link, and its sources, are set out on that condition page.
Does having rs41444548 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs41444548 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
5 32111722315Reads by AI crawlersClaude1ChatGPT0Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3Others15Total32Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Mean corpuscular volume (rs41444548). MyGeneLog™. https://www.mygenelog.com/variants/rs41444548