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Who was studied 20,352 European ancestry bipolar disorder cases, 31,358 European ancestry controls, 322,154 European ancestry individuals with BMI data..
The effect
Each copy of the T allele shifted the measure 0.029 higher (95% confidence interval 0.019-0.039); p = 2 × 10−9.
Where it sits Chromosome 6, band 6p12.3 — between genes, 65.6 kb from FTH1P5.
What each result means
C/CNo copy of the version the research linked to Bipolar disorder or body mass index. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Bipolar disorder or body mass index. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Bipolar disorder or body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Translational psychiatry · 2019 · PMID 31754094 · open access
Questions about rs4141973
What is rs4141973?
rs4141973 is a single position in the genome, in or near the near FTH1P5 gene. Published research associates it with bipolar disorder or body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4141973 linked to?
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs4141973 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4141973 come from?
GWAS Catalog, Translational psychiatry 2019, PMID:31754094. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Bipolar disorder or body mass index (rs4141973). MyGeneLog™. https://www.mygenelog.com/variants/rs4141973