Standard
Acute lymphoblastic leukemia (childhood)
IKZF1 · rs4132601
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Acute lymphoblastic leukemia (childhood) compared to the general population.
G/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Acute lymphoblastic leukemia (childhood).
T/T
Published research associates this genotype with typical/baseline likelihood of Acute lymphoblastic leukemia (childhood) — no copies of the reported risk allele.
Source
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia
Ellinghaus E,
Stanulla M,
Richter G,
Ellinghaus D,
te Kronnie G,
Cario G,
Cazzaniga G,
Horstmann M,
Panzer Grümayer R,
Cavé H,
Trka J,
Cinek O
and 15 more — show all
Teigler-Schlegel A,
ElSharawy A,
Häsler R,
Nebel A,
Meissner B,
Bartram T,
Lescai F,
Franceschi C,
Giordan M,
Nürnberg P,
Heinzow B,
Zimmermann M,
Schreiber S,
Schrappe M,
Franke A
Leukemia · 2012 · PMID 22076464 · open access
Questions about rs4132601
What is rs4132601?
rs4132601 is a single position in the genome, in or near the IKZF1 gene. Published research associates it with acute lymphoblastic leukemia (childhood). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4132601 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4132601 come from?
GWAS Catalog, Leukemia 2011, PMID:22076464. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants