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Immunoglobulin N-glycan 22 levels

near FUT8 · rs4131097

What the study found

Who was studied 2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals.

The effect Each copy of the C allele shifted the measure 0.225 higher (95% confidence interval 0.15-0.3); p = 4 × 10−10.

How common The C allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 14, band 14q23.3 — between genes, 48.3 kb from FUT8.

What each result means

C/C Two copies of the version the research linked to Immunoglobulin N-glycan 22 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Immunoglobulin N-glycan 22 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Immunoglobulin N-glycan 22 levels. This is the starting point the study compared everyone against.
Source

Questions about rs4131097

What is rs4131097?

rs4131097 is a single position in the genome, in or near the near FUT8 gene. Published research associates it with immunoglobulin n-glycan 22 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4131097 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4131097 come from?

GWAS Catalog, Nature communications 2022, PMID:35332118. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Immunoglobulin N-glycan 22 levels (rs4131097). MyGeneLog™. https://www.mygenelog.com/variants/rs4131097

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