Standard

Creatinine levels

GOLPH3L · rs41305070

Where this position leads

Condition: Kidney Function

rs41305070 Condition: Kidney Function Kidney Function Condition rs41305070 rs41305070 GOLPH3L

What the study found

Who was studied 110,051 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0366 higher (95% confidence interval 0.028-0.045); p = 4 × 10−17.

How common The A allele had a frequency of about 79% in the people studied.

Where it sits Chromosome 1, band 1q21.3 — in an intron of GOLPH3L.

What each result means

A/A Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
Source

Questions about rs41305070

What is rs41305070?

rs41305070 is a single position in the genome, in or near the GOLPH3L gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs41305070 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs41305070 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs41305070 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatinine levels (rs41305070). MyGeneLog™. https://www.mygenelog.com/variants/rs41305070

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