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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 531,774 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0695 SD unit lower (95% confidence interval 0.065-0.074); p = 4 × 10−220.
How common The G allele had a frequency of about 76% in the people studied.
Where it sits Chromosome 3, band 3q29 — in an intron of TFRC.
What ClinVar records
ClassificationBenign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 3 submitters), last evaluated 2023-11-12.
ClinVar record 1287653NM_001128148.3(TFRC):c.-23-28C>T
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ANo copy of the version the research linked to Red cell distribution width. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Red cell distribution width. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Red cell distribution width. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs41300435 is a single position in the genome, in or near the TFRC gene. Published research associates it with red cell distribution width. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs41300435 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs41300435 come from?
GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Red cell distribution width (rs41300435). MyGeneLog™. https://www.mygenelog.com/variants/rs41300435