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Who was studied 6,683 European ancestry cases, 12,173 European ancestry controls, 2,601 European ancestry affected sibling pair families, 69 European ancestry trios.
The effect
Each copy of the C allele carried 2.04 times the odds of Type 1 diabetes (95% confidence interval -); p = 5 × 10−8.
How common The C allele had a frequency of about 99% in the people studied.
Where it sits Chromosome 10, band 10p15.1 — inside RBM17.
What each result means
C/CTwo copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
Nature genetics · 2015 · PMID 25751624 · open access
Questions about rs41295121
What is rs41295121?
rs41295121 is a single position in the genome, in or near the IL2RA gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs41295121 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs41295121 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs41295121 come from?
GWAS Catalog, Nat Genet 2015, PMID:25751624. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 1 diabetes (rs41295121). MyGeneLog™. https://www.mygenelog.com/variants/rs41295121