Gene Knowledge Graph
UTC
Standard

Takes medication for Skin condition (ex. Eczema, Psoriasis)?

near RPL32P23 · rs41295071

Where this position leads

Condition: Psoriasis

rs41295071 Condition: Psoriasis Psoriasis Condition rs41295071 rs41295071 near RPL32P23

What the study found

Who was studied 3,695 African American or Afro-Caribbean cases, 51,810 African American or Afro-Caribbean controls, 1,700 Hispanic or Latin American cases, 27,614 Hispanic or Latin American controls, 345 East Asian ancestry cases, 3,202 East Asian ancestry controls, 17,897 European ancestry cases, 297,771 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.148 lower (95% confidence interval 0.12-0.18); p = 5 × 10−18.

How common The C allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 10, band 10p15.1 — between genes, 4.2 kb from RPL32P23.

What each result means

C/C Two copies of the version the research linked to Takes medication for Skin condition (ex. Eczema, Psoriasis)?. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Takes medication for Skin condition (ex. Eczema, Psoriasis)?. That is a smaller link than two copies.
T/T No copy of the version the research linked to Takes medication for Skin condition (ex. Eczema, Psoriasis)?. This is the starting point the study compared everyone against.
Source
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, Ho YL, Kim Y, Heise DA, Guare L, Panickan VA, Garcon H, Linares F
and 59 more — show all
Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner DC, Sangar R, Murray M, Wang X, Dochtermann DR, Devineni P, Shi Y, Nandi TN, Assimes TL, Brunette CA, Carroll RJ, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar SK, Joseph J, Kember R, Kranzler H, Kripke CM, Levey D, Luoh SW, Merritt VC, Overstreet C, Deak JD, Grant SFA, Polimanti R, Roussos P, Shakt G, Sun YV, Tsao N, Venkatesh S, Voloudakis G, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao P, O'Donnell CJ, Muralidhar S, Moser J, Casas JP, Bick AG, Zhou W, Cai T, Voight BF, Cho K, Gaziano JM, Madduri RK, Damrauer S, Liao KP
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access

Questions about rs41295071

What is rs41295071?

rs41295071 is a single position in the genome, in or near the near RPL32P23 gene. Published research associates it with takes medication for skin condition (ex. eczema, psoriasis)?. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs41295071 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs41295071 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs41295071 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Takes medication for Skin condition (ex. Eczema, Psoriasis)? (rs41295071). MyGeneLog™. https://www.mygenelog.com/variants/rs41295071

← See all variants