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Leukocyte telomere length

TINF2 · rs41293836

What the study found

Who was studied 16,759 Singaporean Han Chinese ancestry individuals; replicated in 6,337 Singaporean Chinese ancestry individuals, up to 37,505 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.233 lower; p = 2 × 10−42.

Where it sits Chromosome 14, band 14q12 — in an intron of TGM1.

What each result means

C/C Two copies of the version the research linked to Leukocyte telomere length. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Leukocyte telomere length. That is a smaller link than two copies.
T/T No copy of the version the research linked to Leukocyte telomere length. This is the starting point the study compared everyone against.
Source

Questions about rs41293836

What is rs41293836?

rs41293836 is a single position in the genome, in or near the TINF2 gene. Published research associates it with leukocyte telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs41293836 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs41293836 come from?

GWAS Catalog, Nature communications 2019, PMID:31171785. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Leukocyte telomere length (rs41293836). MyGeneLog™. https://www.mygenelog.com/variants/rs41293836

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