Standard

Age at first sexual intercourse

DCC · rs4129322

Where this position leads

Condition: Age at First Sexual Intercourse

rs4129322 Condition: Age at First Sexual Intercourse Age at First Sexual Intercourse Condition rs4129322 rs4129322 DCC

What the study found

Who was studied 59,357 British ancestry males, 66,310 British ancestry females.

The effect Each copy of the A allele shifted the measure 0.0442 higher (95% confidence interval 0.03-0.058); p = 3 × 10−10.

How common The A allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 18, band 18q21.2 — in an intron of DCC.

What each result means

A/A Two copies of the version the research linked to Age at first sexual intercourse. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Age at first sexual intercourse. That is a smaller link than two copies.
G/G No copy of the version the research linked to Age at first sexual intercourse. This is the starting point the study compared everyone against.
Source

Questions about rs4129322

What is rs4129322?

rs4129322 is a single position in the genome, in or near the DCC gene. Published research associates it with age at first sexual intercourse. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4129322 linked to?

On MyGeneLog this position is linked to Age at First Sexual Intercourse. The research behind each link, and its sources, are set out on that condition page.

Does having rs4129322 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4129322 come from?

GWAS Catalog, Nat Genet 2016, PMID:27089180. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age at first sexual intercourse (rs4129322). MyGeneLog™. https://www.mygenelog.com/variants/rs4129322

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