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HMOX1 protein levels

HABP2 · rs41292628

Where this position leads

Condition: Celiac Disease

rs41292628 Condition: Celiac Disease Celiac Disease Condition rs41292628 rs41292628 HABP2

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.268 higher (95% confidence interval 0.19-0.35); p = 1 × 10−12.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 10, band 10q25.3 — a stop-gain change in HABP2.

What each result means

C/C No copy of the version the research linked to HMOX1 protein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to HMOX1 protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to HMOX1 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs41292628

What is rs41292628?

rs41292628 is a single position in the genome, in or near the HABP2 gene. Published research associates it with hmox1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs41292628 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs41292628 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs41292628 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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HMOX1 protein levels (rs41292628). MyGeneLog™. https://www.mygenelog.com/variants/rs41292628

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