Standard

Standing height (UKB data field 50)

near NMBR · rs4128460

Where this position leads

Conditions: Height, Celiac Disease

rs4128460 Condition: Height Height Condition Condition: Celiac Disease Celiac Disease Condition rs4128460 rs4128460 near NMBR

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0189 lower (95% confidence interval 0.016-0.022); p = 1 × 10−54.

How common The G allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 6, band 6q24.1 — between genes, 23.5 kb from NMBR.

What each result means

A/A No copy of the version the research linked to Standing height (UKB data field 50). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Standing height (UKB data field 50). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Standing height (UKB data field 50). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4128460

What is rs4128460?

rs4128460 is a single position in the genome, in or near the near NMBR gene. Published research associates it with standing height (ukb data field 50). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4128460 linked to?

On MyGeneLog this position is linked to Height, Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs4128460 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4128460 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Standing height (UKB data field 50) (rs4128460). MyGeneLog™. https://www.mygenelog.com/variants/rs4128460

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