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Asthma

PRKCQ-AS1 · rs41284471

Where this position leads

Condition: Asthma

rs41284471 Condition: Asthma Asthma Condition rs41284471 rs41284471 PRKCQ-AS1

What the study found

Who was studied 394,626 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0552 higher (95% confidence interval 0.038-0.072); p = 2 × 10−11.

How common The A allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 10, band 10p15.1 — in an intron of PRKCQ-AS1.

What each result means

A/A Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Asthma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
Source
A scalable variational inference approach for increased mixed-model association power
Loya H, Kalantzis G, Cooper F, Palamara PF
Nature genetics · 2025 · PMID 39789286 · open access

Questions about rs41284471

What is rs41284471?

rs41284471 is a single position in the genome, in or near the PRKCQ-AS1 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs41284471 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs41284471 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs41284471 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs41284471). MyGeneLog™. https://www.mygenelog.com/variants/rs41284471

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