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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 35,292 European ancestry individuals, 227 African ancestry individuals, 380 South Asian ancestry individuals, 115 East Asian ancestry individuals, 338 individuals.
The effect
Each copy of the G allele shifted the measure 0.393 lower (95% confidence interval 0.27-0.52); p = 2 × 10−9.
Where it sits Chromosome 8, band 8p23.1 — in an intron of TNKS.
What each result means
G/GTwo copies of the version the research linked to Anterior amygdaloid area volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Anterior amygdaloid area volume. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Anterior amygdaloid area volume. This is the starting point the study compared everyone against.
Biological psychiatry · 2024 · PMID 37391117 · open access
Questions about rs4128198
What is rs4128198?
rs4128198 is a single position in the genome, in or near the TNKS gene. Published research associates it with anterior amygdaloid area volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4128198 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4128198 come from?
GWAS Catalog, Biological psychiatry 2024, PMID:37391117. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Anterior amygdaloid area volume (rs4128198). MyGeneLog™. https://www.mygenelog.com/variants/rs4128198