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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 38,229 Danish, Icelandic ancestry individuals.
The effect
The reported allele is C; the catalogue records no effect size
; p = 9 × 10−35.
How common The C allele had a frequency of about 95% in the people studied.
Where it sits Chromosome 13, band 13q32.3 — a stop-gain change in CLYBL.
What each result means
C/CTwo copies of the version the research linked to Vitamin B12 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Vitamin B12 levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Vitamin B12 levels. This is the starting point the study compared everyone against.
PLoS genetics · 2013 · PMID 23754956 · open access
Questions about rs41281112
What is rs41281112?
rs41281112 is a single position in the genome, in or near the CLYBL gene. Published research associates it with vitamin b12 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs41281112 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs41281112 come from?
GWAS Catalog, PLoS genetics 2013, PMID:23754956. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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