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Red blood cell count

KIF1B · rs41274456

What the study found

Who was studied 350,475 European ancestry individuals, 153,512 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0381 higher (95% confidence interval 0.028-0.048); p = 1 × 10−13.

Where it sits Chromosome 1, band 1p36.22 — in an intron of KIF1B.

What each result means

C/C No copy of the version the research linked to Red blood cell count. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Red blood cell count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Red blood cell count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs41274456

What is rs41274456?

rs41274456 is a single position in the genome, in or near the KIF1B gene. Published research associates it with red blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs41274456 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs41274456 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Red blood cell count (rs41274456). MyGeneLog™. https://www.mygenelog.com/variants/rs41274456

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