Standard

Telomere length

ZNF676 · rs412658

Where this position leads

Condition: Telomere Length and Epigenetic Age Acceleration

rs412658 Condition: Telomere Length and Epigenetic Age Acceleration Telomere Length and Epigenetic Age … Condition rs412658 rs412658 ZNF676

What the study found

Who was studied 9,190 European ancestry individuals; replicated in 2,226 individuals.

The effect Each copy of the T allele shifted the measure 0.0497 higher (95% confidence interval 0.032-0.067); p = 1 × 10−8.

How common The T allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 19, band 19p12 — between genes, 1.4 kb from VN1R85P.

What each result means

C/C No copy of the version the research linked to Telomere length. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Telomere length. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Telomere length. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs412658

What is rs412658?

rs412658 is a single position in the genome, in or near the ZNF676 gene. Published research associates it with telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs412658 linked to?

On MyGeneLog this position is linked to Telomere Length and Epigenetic Age Acceleration. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs412658?

Subjects that appear in the title or abstract of the same papers as this rsID include short-sightedness and screens (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs412658 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs412658 come from?

GWAS Catalog, Hum Mol Genet 2012, PMID:23001564. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Telomere length (rs412658). MyGeneLog™. https://www.mygenelog.com/variants/rs412658

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