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Afamin levels

AFM · rs41265665

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.865 lower (95% confidence interval 0.76-0.97); p = 4 × 10−54.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 4, band 4q13.3 — a missense change in AFM.

What each result means

A/A Two copies of the version the research linked to Afamin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Afamin levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Afamin levels. This is the starting point the study compared everyone against.
Source

Questions about rs41265665

What is rs41265665?

rs41265665 is a single position in the genome, in or near the AFM gene. Published research associates it with afamin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs41265665 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs41265665 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Afamin levels (rs41265665). MyGeneLog™. https://www.mygenelog.com/variants/rs41265665

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