Sensitive

Plasma cysteinylglycine disulfide* levels in chronic kidney disease

DPEP1 · rs409170

What the study found

Who was studied 4,960 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.122 lower (95% confidence interval 0.11-0.14); p = 3 × 10−72.

How common The G allele had a frequency of about 60% in the people studied.

Where it sits Chromosome 16, band 16q24.3 — in an intron of DPEP1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Plasma cysteinylglycine disulfide* levels in chronic kidney disease — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Plasma cysteinylglycine disulfide* levels in chronic kidney disease.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Plasma cysteinylglycine disulfide* levels in chronic kidney disease compared to the general population.
Source

Questions about rs409170

What is rs409170?

rs409170 is a single position in the genome, in or near the DPEP1 gene. Published research associates it with plasma cysteinylglycine disulfide* levels in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs409170 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs409170 come from?

GWAS Catalog, Nature genetics 2023, PMID:37277652. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Plasma cysteinylglycine disulfide* levels in chronic kidney disease (rs409170). MyGeneLog™. https://www.mygenelog.com/variants/rs409170

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