Standard

diastolic blood pressure (DBP, mean, inv-normal transformed)

near PFKFB4 · rs4075082

Where this position leads

Condition: Blood Pressure

rs4075082 Condition: Blood Pressure Blood Pressure Condition rs4075082 rs4075082 near PFKFB4

What the study found

Who was studied 119,332 African American or Afro-Caribbean individuals.

The effect Each copy of the G allele shifted the measure 0.04 lower (95% confidence interval 0.031-0.049); p = 2 × 10−18.

How common The G allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 3, band 3p21.31 — between genes, 0 kb from PFKFB4.

What each result means

C/C No copy of the version the research linked to diastolic blood pressure (DBP, mean, inv-normal transformed). This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to diastolic blood pressure (DBP, mean, inv-normal transformed). That is a smaller link than two copies.
G/G Two copies of the version the research linked to diastolic blood pressure (DBP, mean, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4075082

What is rs4075082?

rs4075082 is a single position in the genome, in or near the near PFKFB4 gene. Published research associates it with diastolic blood pressure (dbp, mean, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4075082 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs4075082 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4075082 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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diastolic blood pressure (DBP, mean, inv-normal transformed) (rs4075082). MyGeneLog™. https://www.mygenelog.com/variants/rs4075082

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