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Migraine

DYRK3 · rs4074957

Where this position leads

Condition: Migraine

rs4074957 Condition: Migraine Migraine Condition rs4074957 rs4074957 DYRK3

What the study found

Who was studied 85,726 European ancestry cases, 803,292 European ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 2 × 10−9.

How common The C allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 1, band 1q32.1 — inside DYRK3.

What each result means

C/C Two copies of the version the research linked to Migraine. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Migraine. That is a smaller link than two copies.
T/T No copy of the version the research linked to Migraine. This is the starting point the study compared everyone against.
Source

Questions about rs4074957

What is rs4074957?

rs4074957 is a single position in the genome, in or near the DYRK3 gene. Published research associates it with migraine. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4074957 linked to?

On MyGeneLog this position is linked to Migraine. The research behind each link, and its sources, are set out on that condition page.

Does having rs4074957 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4074957 come from?

GWAS Catalog, Communications biology 2021, PMID:34294844. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Migraine (rs4074957). MyGeneLog™. https://www.mygenelog.com/variants/rs4074957

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