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Who was studied 684,122 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.025 lower; p = 2 × 10−23.
Where it sits Chromosome 3, band 3p25.2 — in an intron of PPARG.
What each result means
A/ANo copy of the version the research linked to Hemoglobin levels. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Hemoglobin levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2020 · PMID 32327693 · open access
Questions about rs4073770
What is rs4073770?
rs4073770 is a single position in the genome, in or near the PPARG gene. Published research associates it with hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4073770 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs4073770 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4073770 come from?
GWAS Catalog, Communications biology 2020, PMID:32327693. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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