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Asthma

STAT5B · rs4029774

Where this position leads

Condition: Asthma

rs4029774 Condition: Asthma Asthma Condition rs4029774 rs4029774 STAT5B

What the study found

Who was studied 38,369 European ancestry cases, 411,131 European ancestry controls, 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0493 lower (95% confidence interval 0.035-0.064); p = 6 × 10−11.

Where it sits Chromosome 17, band 17q21.2 — inside STAT5B.

What each result means

A/A No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Asthma. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4029774

What is rs4029774?

rs4029774 is a single position in the genome, in or near the STAT5B gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4029774 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs4029774 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4029774 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs4029774). MyGeneLog™. https://www.mygenelog.com/variants/rs4029774

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