Sensitive

Bipolar disorder or ulcerative colitis (MTAG)

H2AC14 · rs401763

Where this position leads

Condition: Ulcerative Colitis

rs401763 Condition: Ulcerative Colitis Ulcerative Colitis Condition rs401763 rs401763 H2AC14

What the study found

Who was studied 41,917 European ancestry bipolar disorder cases, 12,366 European ancestry ulcerative colitis cases, 405,158 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.025 higher (95% confidence interval 0.017-0.033); p = 2 × 10−11.

Where it sits Chromosome 6, band 6p22.1 — in the 5′ untranslated region of H2AC14.

What each result means

C/C No copy of the version the research linked to Bipolar disorder or ulcerative colitis (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Bipolar disorder or ulcerative colitis (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Bipolar disorder or ulcerative colitis (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs401763

What is rs401763?

rs401763 is a single position in the genome, in or near the H2AC14 gene. Published research associates it with bipolar disorder or ulcerative colitis (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs401763 linked to?

On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs401763 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs401763 come from?

GWAS Catalog, Journal of affective disorders 2024, PMID:38154582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Bipolar disorder or ulcerative colitis (MTAG) (rs401763). MyGeneLog™. https://www.mygenelog.com/variants/rs401763

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