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Body size at age 10

TRAF3 · rs3993347

What the study found

Who was studied 453,169 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.00861 higher (95% confidence interval 0.0057-0.0115); p = 4 × 10−9.

How common The T allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 14, band 14q32.32 — in an intron of TRAF3.

What each result means

C/C No copy of the version the research linked to Body size at age 10. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Body size at age 10. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body size at age 10. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3993347

What is rs3993347?

rs3993347 is a single position in the genome, in or near the TRAF3 gene. Published research associates it with body size at age 10. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3993347 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3993347 come from?

GWAS Catalog, BMJ (Clinical research ed.) 2020, PMID:32376654. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body size at age 10 (rs3993347). MyGeneLog™. https://www.mygenelog.com/variants/rs3993347

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