Standard

Creatinine levels

SLC9B1 · rs3974479

Where this position leads

Condition: Kidney Function

rs3974479 Condition: Kidney Function Kidney Function Condition rs3974479 rs3974479 SLC9B1

What the study found

Who was studied 110,051 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0275 higher (95% confidence interval 0.02-0.034); p = 1 × 10−14.

How common The A allele had a frequency of about 52% in the people studied.

Where it sits Chromosome 4, band 4q24 — in an intron of SLC9B1.

What each result means

A/A Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
Source

Questions about rs3974479

What is rs3974479?

rs3974479 is a single position in the genome, in or near the SLC9B1 gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3974479 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs3974479 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3974479 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Creatinine levels (rs3974479). MyGeneLog™. https://www.mygenelog.com/variants/rs3974479

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