0 293216222110Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 14,802 European and unknown ancestry cases, 26,703 European and unknown ancestry controls; replicated in 32,627 European and unknown ancestry cases, 41,672 European and unknown ancestry controls.
The effect
Each copy of the T allele carried 1.06 times the odds of Multiple sclerosis; p = 2 × 10−8.
Where it sits Chromosome 8, band 8q24.3 — between genes, 2.5 kb from PLEC.
What each result means
C/CNo copy of the version the research linked to Multiple sclerosis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Multiple sclerosis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Multiple sclerosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs3923387 is a single position in the genome, in or near the EPPK1 gene. Published research associates it with multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3923387 linked to?
On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs3923387 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3923387 come from?
GWAS Catalog, Science 2019, PMID:31604244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 293216222110Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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