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IDP dMRI TBSS L3 Anterior limb of internal capsule R

near RPS26P8 · rs391338

What the study found

Who was studied 20,860 British ancestry individuals; replicated in 10,496 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.099 higher (95% confidence interval 0.075-0.123); p = 5 × 10−17.

How common The A allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 17, band 17q21.31 — between genes, 1 kb from RPS26P8.

What each result means

A/A Two copies of the version the research linked to IDP dMRI TBSS L3 Anterior limb of internal capsule R. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to IDP dMRI TBSS L3 Anterior limb of internal capsule R. That is a smaller link than two copies.
G/G No copy of the version the research linked to IDP dMRI TBSS L3 Anterior limb of internal capsule R. This is the starting point the study compared everyone against.
Source

Questions about rs391338

What is rs391338?

rs391338 is a single position in the genome, in or near the near RPS26P8 gene. Published research associates it with idp dmri tbss l3 anterior limb of internal capsule r. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs391338 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs391338 come from?

GWAS Catalog, Nature neuroscience 2021, PMID:33875891. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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IDP dMRI TBSS L3 Anterior limb of internal capsule R (rs391338). MyGeneLog™. https://www.mygenelog.com/variants/rs391338

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