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LPA protein levels

SLC22A2 · rs3912160

Where this position leads

Condition: Celiac Disease

rs3912160 Condition: Celiac Disease Celiac Disease Condition rs3912160 rs3912160 SLC22A2

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.257 higher (95% confidence interval 0.23-0.28); p = 2 × 10−88.

How common The A allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 6, band 6q25.3 — in an intron of SLC22A2.

What each result means

A/A Two copies of the version the research linked to LPA protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to LPA protein levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to LPA protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs3912160

What is rs3912160?

rs3912160 is a single position in the genome, in or near the SLC22A2 gene. Published research associates it with lpa protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3912160 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs3912160 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3912160 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

LPA protein levels (rs3912160). MyGeneLog™. https://www.mygenelog.com/variants/rs3912160

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