0 2616223210Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others10Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 9,240 European ancestry broad depression cases, 9,519 European ancestry broad depression controls, 51,258 European ancestry individuals, 36,989 European and East Asian ancestry schizophrenia cases, 113,075 European and East Asian ancestry schizophrenia controls; replicated in 322,580 individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 1 × 10−12.
How common The T allele had a frequency of about 68% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of WHR1.
What each result means
G/GNo copy of the version the research linked to Broad depression or schizophrenia. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Broad depression or schizophrenia. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Broad depression or schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Molecular psychiatry · 2020 · PMID 30626913 · open access
Questions about rs389883
What is rs389883?
rs389883 is a single position in the genome, in or near the STK19 gene. Published research associates it with broad depression or schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs389883 linked to?
On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.
Does having rs389883 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs389883 come from?
GWAS Catalog, Mol Psychiatry 2019, PMID:30626913. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2616223210Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others10Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Broad depression or schizophrenia (rs389883). MyGeneLog™. https://www.mygenelog.com/variants/rs389883