A/APublished research associates this genotype with typical/baseline likelihood of Graves' disease — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Graves' disease.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Graves' disease compared to the general population.
rs3893464 is a single position in the genome, in or near the MHC gene. Published research associates it with graves' disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3893464 linked to?
On MyGeneLog this position is linked to Graves' Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs3893464 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3893464 come from?
GWAS Catalog, J Hum Genet 2011, PMID:21900946. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.