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Testosterone levels

ZBTB4 · rs3867595

What the study found

Who was studied 4,291 European ancestry men, 3,352 European ancestry women.

The effect Each copy of the C allele shifted the measure 0.231 lower (95% confidence interval 0.15-0.31); p = 1 × 10−8.

How common The C allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 17, band 17p13.1 — in an intron of ZBTB4.

What each result means

C/C Two copies of the version the research linked to Testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Testosterone levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Testosterone levels. This is the starting point the study compared everyone against.
Source

Questions about rs3867595

What is rs3867595?

rs3867595 is a single position in the genome, in or near the ZBTB4 gene. Published research associates it with testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3867595 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3867595 come from?

GWAS Catalog, The Journal of clinical endocrinology and metabolism 2019, PMID:31169883. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Testosterone levels (rs3867595). MyGeneLog™. https://www.mygenelog.com/variants/rs3867595

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