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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 4,642 European ancestry women.
The effect
Each copy of the T allele shifted the measure 0.494 higher (95% confidence interval 0.39-0.6); p = 6 × 10−20.
Where it sits Chromosome 14, band 14q23.2 — in an intron of SYNE2.
What each result means
A/ANo copy of the version the research linked to Sphingomyelin (d32:1) levels. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Sphingomyelin (d32:1) levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Sphingomyelin (d32:1) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Journal of the American Heart Association · 2022 · PMID 36193934 · open access
Questions about rs3866736
What is rs3866736?
rs3866736 is a single position in the genome, in or near the SYNE2 gene. Published research associates it with sphingomyelin (d32:1) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3866736 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3866736 come from?
GWAS Catalog, Journal of the American Heart Association 2022, PMID:36193934. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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