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Who was studied 22,474 European ancestry cases, 774,187 European ancestry controls.
The effect
Each copy of the T allele carried 0.93 times the odds of Atopic dermatitis (95% confidence interval 0.91-0.95); p = 4 × 10−12.
How common The T allele had a frequency of about 31% in the people studied.
Where it sits Chromosome 16, band 16p13.13 — in an intron of CLEC16A.
What each result means
C/CNo copy of the version the research linked to Atopic dermatitis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Atopic dermatitis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Atopic dermatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of allergy and clinical immunology · 2022 · PMID 34454985
Questions about rs3862469
What is rs3862469?
rs3862469 is a single position in the genome, in or near the CLEC16A gene. Published research associates it with atopic dermatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3862469 linked to?
On MyGeneLog this position is linked to Atopic Dermatitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs3862469 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3862469 come from?
GWAS Catalog, The Journal of allergy and clinical immunology 2022, PMID:34454985. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1722112Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others12Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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